Protein Family Models for Protein (Select 1055322798) - Protein Family Models

Select item 4247131.

Date:: 2024-08-14

Family Accession:: NF027681.5
Method:: HMM

Select item 4123802.

NAD-dependent epimerase/dehydratase family protein

This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions. [1]. 9174344. Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli. Thoden JB, Hegeman AD, Wesenberg G, Chapeau MC, Frey PA, Holden HM;. Biochemistry 1997;36:6294-6304. (from Pfam)

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Date:: 2024-10-16

Family Accession:: NF013530.5
Method:: HMM

Select item 4039773.

new record, indexing in progress

Family Accession:

Select item 3890054.

new record, indexing in progress

Family Accession:

Select item 3599925.

new record, indexing in progress

Family Accession:

Select item 3483646.

new record, indexing in progress

Family Accession:

Select item 1414697.

GDP-mannose 4,6-dehydratase

Alternate name: GDP-D-mannose dehydratase. This enzyme converts GDP-mannose to GDP-4-dehydro-6-deoxy-D-mannose, the first of three steps for the conversion of GDP-mannose to GDP-fucose in animals, plants, and bacteria. In bacteria, GDP-L-fucose acts as a precursor of surface antigens such as the extracellular polysaccharide colanic acid of E. coli. Excluded from this model are members of the clade that score poorly because of highly dervied (phylogenetically long-branch) sequences, e.g. Aneurinibacillus thermoaerophilus Gmd, described as a bifunctional GDP-mannose 4,6-dehydratase/GDP-6-deoxy-D-lyxo-4-hexulose reductase (PUBMED:11096116).

Gene:: gmd

GO Terms:

Biological Process:: polysaccharide biosynthetic process (GO:0000271)

Molecular Function:: GDP-mannose 4,6-dehydratase activity (GO:0008446)

Biological Process:: GDP-mannose metabolic process (GO:0019673)

Date:: 2024-06-24

Family Accession:: TIGR01472.1
Method:: HMM

Select item 818628.

GDP-mannose 4,6-dehydratase

GDP-mannose 4,6-dehydratase catalyzes the NADP(H)-dependent conversion of GDP-(D)-mannose to GDP-4-keto, 6-deoxy-(D)-mannose in the fucose biosynthesis pathway

Date:: 2024-07-03

Family Accession:: 10787214
Method:: Sparcle

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