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SPFH domain-containing protein
This family has been called SPFH [1], Band 7 or PHB domain. Recent phylogenetic analysis has shown this domain to be a slipin or Stomatin-like integral membrane domain conserved from protozoa to mammals. [1]. 10542406. The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins. Tavernarakis N, Driscoll M, Kyrpides NC;. Trends Biochem Sci 1999;24:425-427. [2]. 18267007. Slipins: ancient origin, duplication and diversification of the stomatin protein family. Green JB, Young JP;. BMC Evol Biol. 2008;8:44. (from Pfam)
SPFH (stomatin, prohibitin, flotillin, and HflK/C) domain-containing protein similar to Homo sapiens mitochondrial stomatin-like protein 2, and Escherichia coli protein QmcA
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