Protein Family Models

This domain is found in found in uncharacterised proteins predominantly from bacteria. The uncharacterised Swiss:Q9I1U6 from Pseudomonas aeruginosa shows a ferritin-like topology with a four-helix-bundle fold that lacks metal-ion-binding site typical of the ferritin family (Pfam:PF00210) but has a potential metal-binding site [1]. The function is unknown. [1]. 23295481. The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery. Moynie L, Schnell R, McMahon SA, Sandalova T, Boulkerou WA, Schmidberger JW, Alphey M, Cukier C, Duthie F, Kopec J, Liu H, Jacewicz A, Hunter WN, Naismith JH, Schneider G;. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013;69:25-34. (from Pfam)

Date:

2024-10-16

ferritin-like domain-containing protein belongs to a broad superfamily of ferritin-like diiron-carboxylate proteins that catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; similar to Pseudomonas aeruginosa PA2169

Date:

2024-11-18