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type I toxin-antitoxin system toxin Ldr family protein
This family includes the Ldr (long direct repeat) toxins. In Escherichia coli there are four Ldr toxins, LdrA, LdrB, LdrC and LdrD. These toxins inhibit cell growth, decrease cell viability and cause nucleoid condensation. LdrD expression is inhibited by the antisense RNA RdlD, which functions as an antitoxin [1]. [1]. 12123448. Molecular characterization of long direct repeat (LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cis-encoded small antisense RNA in Escherichia coli. Kawano M, Oshima T, Kasai H, Mori H;. Mol Microbiol. 2002;45:333-349. (from Pfam)
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