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CocE/NonD family hydrolase C-terminal non-catalytic domain-containing protein
This domain contains a beta sandwich domain. (from Pfam)
CocE/NonD family hydrolase
CocE/NonD family hydrolase similar to Rhodococcus sp. cocaine esterase that hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth
This model represents a protein subfamily that includes the cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). This family shows extensive, low-level similarity to a family of xaa-pro dipeptidyl-peptidases, and local similarity by PSI-BLAST to many other hydrolases.
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