Protein Family Models for Protein (Select 1168747328) - Protein Family Models

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Items: 6

Select item 4182781.

MFS transporter

GO Terms:

Molecular Function:: transmembrane transporter activity (GO:0022857)

Biological Process:: transmembrane transport (GO:0055085)

Date:: 2024-08-14

Family Accession:: NF019310.5
Method:: HMM

Select item 4134592.

BT1 family

Members of this family are transmembrane proteins. Several are Leishmania putative proteins that are thought to be pteridine transporters. One such protein Swiss:Q25272, previously termed (and is still annotated as) ORFG, was shown to encode a biopterin transport protein using null mutants [1], thus being subsequently renamed BT1. The significant similarity of ORFG/BT1 to Trypanosoma brucei ESAG10 (a putative transmembrane protein and another member of this family) was previously noted [2]. This family also contains five putative Arabidopsis thaliana proteins of unknown function. In addition, it also contains two predicted prokaryotic proteins (from the cyanobacteria Synechocystis and Synechococcus). [1]. 10589984. The Leishmania donovani LD1 locus gene ORFG encodes a biopterin. transporter (BT1).. Lemley C, Yan S, Dole VS, Madhubala R, Cunningham ML, Beverley. SM, Myler PJ, Stuart KD;. Mol Biochem Parasitol 1999;104:93-105.. [2]. 7984172. An amplified DNA element in Leishmania encodes potential. integral membrane and nucleotide-binding proteins.. Myler PJ, Lodes MJ, Merlin G, de Vos T, Stuart KD;. Mol Biochem Parasitol 1994;66:11-20. (from Pfam)