Protein Family Models for Protein (Select 1197222019) - Protein Family Models

Select item 4123531.

This family consists of various hypothetical proteins and an l-lysine exporter LysE Swiss:P94633 from Corynebacterium glutamicum which is proposed to be the first of a novel family of translocators [1]. LysE exports l-lysine from the cell into the surrounding medium and is predicted to span the membrane six times [1]. The physiological function of the exporter is to excrete excess l-Lysine as a result of natural flux imbalances or peptide hydrolysis; and also after artificial deregulation of l-Lysine biosynthesis as used by the biotechnology. industry for the production of l-lysine [1]. [1]. 8971704. A new type of transporter with a new type of cellular function: L- lysine export from Corynebacterium glutamicum. Vrljic M, Sahm H, Eggeling L;. Mol Microbiol 1996;22:815-826. [2]. 10322417. A new family of amino-acid-efflux proteins. Aleshin VV, Zakataeva NP, Livshits VA;. Trends Biochem Sci 1999;24:133-135. (from Pfam)

GO Terms:

Biological Process:: amino acid transport (GO:0006865)

Cellular Component:: membrane (GO:0016020)

Date:: 2024-10-16

Family Accession:: NF013933.5
Method:: HMM

Select item 3888812.

new record, indexing in progress

Family Accession:

Select item 3473003.

new record, indexing in progress

Family Accession:

Select item 1753684.

LysE family translocator

LysE family translocator is involved in the efflux of one or more of a variety of biologically important solutes such as L-lysine, threonine, or homoserine

Date:: 2024-04-14

Family Accession:: 10003423
Method:: Sparcle

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