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class I tRNA ligase family protein
This family includes methionyl tRNA synthetases. (from Pfam)
tRNA synthetases class I (K)
This family includes only lysyl tRNA synthetases from prokaryotes. [1]. 9353192. A euryarchaeal lysyl-tRNA synthetase: resemblance to class I synthetases. Ibba M, Morgan S, Curnow AW, Pridmore DR, Vothknecht UC, Gardner W, Lin W, Woese CR, Soll D;. Science 1997;278:1119-1122. (from Pfam)
lysine--tRNA ligase
lysine--tRNA ligase catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA(Lys)
This model represents the lysyl-tRNA synthetases that are class I amino-acyl tRNA synthetases. It includes archaeal and spirochete examples of the enzyme. All other known examples are class IIc amino-acyl tRNA synthetases and seem to form a separate orthologous set.
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