Protein Family Models

This family of proteins is involved in spore coat assembly during the process of sporulation [1]. Proteins in this family consist of five anti-parallel beta strands [2]. [1]. 15231775. Dynamic patterns of subcellular protein localization during spore coat morphogenesis in Bacillus subtilis. van Ooij C, Eichenberger P, Losick R;. J Bacteriol 2004;186:4441-4448. [2]. 21904870. Solution NMR structure of Dsy0195 homodimer from Desulfitobacterium hafniense: first structure representative of the YabP domain family of proteins involved in spore coat assembly. Yang Y, Ramelot TA, Cort JR, Wang H, Ciccosanti C, Jiang M, Janjua H, Acton TB, Xiao R, Everett JK, Montelione GT, Kennedy MA;. J Struct Funct Genomics. 2011;12:175-179. (from Pfam)

Date:

2024-10-16

Members of this protein family are the YabP protein of the bacterial sporulation program, as found in Bacillus subtilis, Clostridium tetani, and other spore-forming members of the Firmicutes. In Bacillus subtilis, a yabP single mutant appears to sporulate and germinate normally (PMID:11283287), but is in an operon with yabQ (essential for formation of the spore cortex), it near-universal among endospore-forming bacteria, and is found nowhere else. It is likely, therefore, that YabP does have a function in sporulation or germination, one that is either unappreciated or partially redundant with that of another protein.

Gene:

yabP

Date:

2024-06-26