Protein Family Models

This family consists of several bacterial proteins which are homologous to the oligogalacturonate-specific porin protein KdgM (Swiss:Q934G3) from Erwinia chrysanthemi. The phytopathogenic Gram-negative bacteria Erwinia chrysanthemi secretes pectinases, which are able to degrade the pectic polymers of plant cell walls, and uses the degradation products as a carbon source for growth. KdgM is a major outer membrane protein, whose synthesis is strongly induced in the presence of pectic derivatives. KdgM behaves like a voltage-dependent porin that is slightly selective for anions and that exhibits fast block in the presence of trigalacturonate. In contrast to most porins, KdgM seems to be monomeric [1]. [1]. 11773048. The oligogalacturonate-specific porin KdgM of Erwinia chrysanthemi belongs to a new porin family. Blot N, Berrier C, Hugouvieux-Cotte-Pattat N, Ghazi A, Condemine G;. J Biol Chem 2002;277:7936-7944. (from Pfam)

Date:

2024-10-16