Protein Family Models

Mal_decarbox_Al is a family of Na+-transporting carboxylic acid decarboxylases. [1]. 18251085. Purification and characterization of a cytoplasmic enzyme component of the Na+-activated malonate decarboxylase system of Malonomonas rubra: acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase. Hilbi H, Dimroth P;. Arch Microbiol. 1994;162:48-56. (from Pfam)

Date:

2024-10-16

malonate decarboxylase subunit alpha acts as an acyl-carrier protein (ACP) transferase component of the biotin-independent and biotin-dependent malonate decarboxylase multienzyme complex, catalyzing the transfer of malonate (substrate) to an ACP subunit for subsequent decarboxylation

Date:

2019-04-17

This model describes malonate decarboxylase alpha subunit, from both the water-soluble form as found in Klebsiella pneumoniae and the form couple to sodium ion pumping in Malonomonas rubra. Malonate decarboxylase Na+ pump is the paradigm of the family of Na+ transport decarboxylases. Essentially, it couples the energy derived from decarboxylation of a carboxylic acid substrate to move Na+ ion across the bilayer. Functional malonate decarboylase is a multi subunit protein. The alpha subunit enzymatically performs the transfer of malonate (substrate) to an acyl carrier protein subunit for subsequent decarboxylation, hence the name: acetyl-S-acyl carrier protein:malonate carrier protein-SH transferase.

Gene:

mdcA

Date:

2024-06-14