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nitrate- and nitrite sensing domain-containing protein
The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure [1]. [1]. 12633990. The NIT domain: a predicted nitrate-responsive module in bacterial sensory receptors. Shu CJ, Ulrich LE, Zhulin IB;. Trends Biochem Sci 2003;28:121-124. (from Pfam)
HAMP domain-containing protein
methyl-accepting chemotaxis protein
This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs. [1]. 1601874. Sequence and characterization of Bacillus subtilis CheW. Hanlon DW, Marquez-Magana LM, Carpenter PB, Chamberlin MJ, Ordal GW;. J Biol Chem 1992;267:12055-12060. (from Pfam)
methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior
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