Protein Family Models for Protein (Select 1369099469) - Protein Family Models

Select item 4321431.

This domain is part of a dehydratase domain found in diverse PKS enzymes. This domain adopts a HotDog fold. Paper describing PDB structure 2vz8. [1]. 18772430. The crystal structure of a mammalian fatty acid synthase. Maier T, Leibundgut M, Ban N;. Science. 2008;321:1315-1322. Paper describing PDB structure 3el6. [2]. 18952099. Crystal structure of the erythromycin polyketide synthase dehydratase. Keatinge-Clay A;. J Mol Biol. 2008;384:941-953. Paper describing PDB structure 3hhd. [3]. 20132826. Structure of the human fatty acid synthase KS-MAT didomain as a framework for inhibitor design. Pappenberger G, Benz J, Gsell B, Hennig M, Ruf A, Stihle M, Thoma R, Rudolph MG;. J Mol Biol. 2010;397:508-519. Paper describing PDB structure 3hrq. [4]. 19847268. Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization. Crawford JM, Korman TP, Labonte JW, Vagstad AL, Hill EA, Kamari-Bidkorpeh O, Tsai SC, Townsend CA;. Nature. 2009;461:1139-1143. Paper describing PDB structure 3kg6. [5]. 20152156. Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway. Akey DL, Razelun JR, Tehranisa J, Sherman DH, Gerwick WH, Smith JL;. Structure. 2010;18:94-105. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF044701.2
Method:: HMM

Select item 4307162.

ketoacyl-synthetase C-terminal extension domain-containing protein

KAsynt_C_assoc represents the very C-terminus of a subset of proteins from the keto-acyl-synthetase 2 family. It is found in proteins ranging from bacteria to human. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF027522.5
Method:: HMM

Select item 4108503.

acyltransferase domain-containing protein

Date:: 2024-08-14

Family Accession:: NF012901.5
Method:: HMM

Select item 4086814.