Protein Family Models

Members of this family are predicted to be bacterial transglutaminase-like cysteine proteinases. They contain a conserved Cys-His-Asp catalytic triad. Their structure is predicted to be similar to that of Salmonella typhimurium N-hydroxyarylamine O-acetyltransferase Swiss:Q00267, in Pfam:PF00797, however they lack the sub-domain which is important for arylamine recognition [1]. [1]. 15288868. BTLCP proteins: a novel family of bacterial transglutaminase-like cysteine proteinases. Ginalski K, Kinch L, Rychlewski L, Grishin NV;. Trends Biochem Sci. 2004;29:392-395. (from Pfam)

Date:

2024-10-16

transglutaminase-like cysteine peptidase contains an invariant Cys-His-Asp catalytic triad and is predicted to possess a papain-like cysteine proteinase fold and to catalyze post-translational protein modification through transamidase, acetylase or hydrolase activity

Date:

2019-08-09