Protein Family Models for Protein (Select 1621464665) - Protein Family Models

Select item 4311511.

prephenate dehydrogenase dimerization domain-containing protein

Members of this family are prephenate dehydrogenases EC:1.3.1.12 (PDHs) involved in tyrosine biosynthesis [1]. This is the C-terminal, helical dimerization domain of PDHs [1]. [1]. 31750992. Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Shabalin IG, Gritsunov A, Hou J, Slawek J, Miks CD, Cooper DR, Minor W, Christendat D;. FEBS J. 2020;287:2235-2255. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF042869.3
Method:: HMM

Select item 4154072.

NAD(P)-binding domain-containing protein

Date:: 2024-08-14

Family Accession:: NF015747.5
Method:: HMM

Select item 4143543.

NAD(P)-binding domain-containing protein

The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold. (from Pfam)

GO Terms:

Molecular Function:: NADP binding (GO:0050661)

Date:: 2024-08-14

Family Accession:: NF015411.5
Method:: HMM

Select item 4116114.

prephenate dehydrogenase/arogenate dehydrogenase family protein

Members of this family are prephenate dehydrogenases (PDHs) EC:1.3.1.12 involved in tyrosine biosynthesis. This is the N-terminal nucleotide-binding domain of PDHs, which has a modified Rossmann nucleotide-binding fold with an extended beta-sheet sandwiched by three helices on each face [1]. [1]. 31750992. Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Shabalin IG, Gritsunov A, Hou J, Slawek J, Miks CD, Cooper DR, Minor W, Christendat D;. FEBS J. 2020;287:2235-2255. (from Pfam)

GO Terms:

Biological Process:: tyrosine biosynthetic process (GO:0006571)

Molecular Function:: prephenate dehydrogenase (NAD+) activity (GO:0008977)

Molecular Function:: arogenate dehydrogenase (NADP+) activity (GO:0033730)

Molecular Function:: NAD+ binding (GO:0070403)

Date:: 2024-10-16

Family Accession:: NF014234.5
Method:: HMM

Select item 4110995.

EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)

GO Terms:

Molecular Function:: transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765)

Date:: 2024-08-14

Family Accession:: NF012497.5
Method:: HMM

Select item 4082286.

new record, indexing in progress

Family Accession:

Select item 3915267.

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Family Accession:

Select item 3914418.

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Family Accession:

Select item 3903219.

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Family Accession:

Select item 38829410.

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Family Accession:

Select item 36649711.

new record, indexing in progress

Family Accession:

Select item 35042712.

new record, indexing in progress

Family Accession:

Select item 34973113.

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Family Accession:

Select item 34785814.

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Family Accession:

Select item 34648915.

new record, indexing in progress

Family Accession:

Select item 33875716.

bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase

Catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate and Catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis

GO Terms:

Molecular Function:: prephenate dehydrogenase (NAD+) activity (GO:0008977)

Biological Process:: aromatic amino acid family biosynthetic process (GO:0009073)

Date:: 2022-07-08

Family Accession:: NF011381.1
Method:: HMM

Select item 26241117.

bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase

Date:: 2019-06-06

Family Accession:: 11487433
Method:: Sparcle

Select item 14144018.

3-phosphoshikimate 1-carboxyvinyltransferase

This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function.

Gene:: aroA

GO Terms:

Molecular Function:: 3-phosphoshikimate 1-carboxyvinyltransferase activity (GO:0003866)

Biological Process:: aromatic amino acid family biosynthetic process (GO:0009073)

Date:: 2024-06-10

Family Accession:: TIGR01356.1
Method:: HMM

Select item 802619.

new record, indexing in progress

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