Protein Family Models

This domain is found as a leader peptide in at least a subset of proteins targeted to the type of exosporium that occurs as the outermost layer of Bacillus anthracis, B. cereus, and B. thuringiensis spores. The exosporium consists of a basal layer and a nap of hair-like filaments. BclA, the major protein of the nap filaments, is targeted there by this leader peptide. In known examples of proteins in this family, the exosporium leader peptide is followed immediately by collagen-like Pro-rich tripeptide repeats. The last six residues of the seed alignment represent the first two PXG repeats.

Date:

2023-12-12