Protein Family Models

This family consists of MuA-transposase and repressor protein CI. These proteins contain homologous DNA-binding domains at their N-termini which compete for the same DNA site within the Mu bacteriophage genome. [1]. 2999776. Primary structure of phage mu transposase: homology to mu repressor. Harshey RM, Getzoff ED, Baldwin DL, Miller JL, Chaconas G;. Proc Natl Acad Sci U S A 1985;82:7676-7680. [2]. 10387082. NMR structure and functional studies of the Mu repressor DNA-binding domain. Ilangovan U, Wojciak JM, Connolly KM, Clubb RT;. Biochemistry 1999;38:8367-8376. (from Pfam)

Date:

2024-10-16

transposase is an enzyme that binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism; similar to Geobacillus stearothermophilus insertion sequence element IS5376

Date:

2016-11-25