Protein Family Models for Protein (Select 1834227294) - Protein Family Models

Select item 4366591.

AraC family transcriptional regulator containing a cupin domain as its effector domain and an AraC family helix-turn-helix (HTH) DNA binding domain, controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

Date:: 2024-11-14

Family Accession:: 15746830
Method:: Sparcle

Select item 4208632.

cupin domain-containing protein

This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024260.5
Method:: HMM

Select item 4206773.

helix-turn-helix domain-containing protein

GO Terms:

Molecular Function:: DNA-binding transcription factor activity (GO:0003700)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Molecular Function:: sequence-specific DNA binding (GO:0043565)

Date:: 2024-08-14

Family Accession:: NF024242.5
Method:: HMM

Select item 4137314.

AraC family ligand binding domain-containing protein

This family represents the arabinose-binding and dimerisation domain of the bacterial gene regulatory protein AraC. The domain is found in conjunction with the helix-turn-helix (HTH) DNA-binding motif Pfam:PF00165. This domain is distantly related to the Cupin domain Pfam:PF00190. [1]. 9103202. Structural basis for ligand-regulated oligomerization of AraC. Soisson SM, MacDougall-Shackleton B, Schleif R, Wolberger C;. Science 1997;276:421-425. (from Pfam)

GO Terms:

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-10-16

Family Accession:: NF014376.5
Method:: HMM

Select item 4012595.