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ElyC/SanA/YdcF family protein
This large family of proteins contains several highly conserved charged amino acids, suggesting this may be an enzymatic domain (Bateman A pers. obs). The family includes SanA Swiss:P33017 that is involved in Vancomycin resistance [1]. This protein may be involved in murein synthesis [2]. [1]. 8550448. Amplification of a novel gene, sanA, abolishes a vancomycin-sensitive defect in Escherichia coli. Rida S, Caillet J, Alix JH;. J Bacteriol 1996;178:94-102. [2]. 9738879. The sfiX, rfe and metN genes of Salmonella typhimurium and their involvement in the His(c) pleiotropic response. Mouslim C, Cano DA, Casadesus J;. Mol Gen Genet 1998;259:46-53. (from Pfam)
YdcF family protein
YdcF family protein is a DUF218 domain-containing protein; similar to Escherichia coli YdcF, which adopts an alpha/beta-fold and binds S-adenosyl-L-methionine (SAM)
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