Protein Family Models for Protein (Select 1859348460) - Protein Family Models

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Links from Protein

Items: 9

Select item 4147081.

Winged helix-turn-helix transcription repressor, HrcA DNA-binding

This domain is always found with a pair of CBS domains Pfam:PF00571. (from Pfam)

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-08-14

Family Accession:: NF015409.5
Method:: HMM

Select item 4123682.

Rrf2 family transcriptional regulator

Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription regulation [1]. The iron binding is mediated by three conserved cysteine residues. Members of this family can also bind O-acetyl-L-serine, [Fe-S] and nitric oxide (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). [1]. 23644595. Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. Rajagopalan S, Teter SJ, Zwart PH, Brennan RG, Phillips KJ, Kiley PJ;. Nat Struct Mol Biol. 2013;20:740-747. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF014173.5
Method:: HMM

Select item 3982833.