Protein Family Models for Protein (Select 1891747471) - Protein Family Models

Select item 4307891.

This entry represents a protein that belongs to the alpha/beta hydrolase superfamily. Although proteins in this family are uncharacterised they are likely to have an enzymatic activity. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF042734.3
Method:: HMM

Select item 4126292.

CocE/NonD family hydrolase

GO Terms:

Molecular Function:: hydrolase activity (GO:0016787)

Date:: 2024-08-14

Family Accession:: NF014215.5
Method:: HMM

Select item 4114993.

thioesterase domain-containing protein

Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to the type II fatty acid thioesterases of vertebrates. There are also modules within the peptide synthetases that also share this similarity. With respect to antibiotic production, thioesterases are required for the addition of the last amino acid to the peptide antibiotic, thereby forming a cyclic antibiotic. Thioesterases (non-integrated) have molecular masses of 25-29 kDa. [1]. 9560421. Genetic evidence for a role of thioesterase domains, integrated in or associated with peptide synthetases, in non-ribosomal peptide biosynthesis in Bacillus subtilis. Schneider A, Marahiel MA;. Arch Microbiol 1998;169:404-410. (from Pfam)

GO Terms:

Biological Process:: biosynthetic process (GO:0009058)

Date:: 2024-10-16

Family Accession:: NF013166.5
Method:: HMM

Select item 4113294.

alpha/beta fold hydrolase

This catalytic domain is found in a very wide range of enzymes. [1]. 1409539. The alpha/beta hydrolase fold. Ollis DL, Cheah E, Cygler M, Dijkstra B, Frolow F, Franken SM, Harel M, Remington SJ, Silman I, Schrag J, Sussman JL, Verschueren KHG, Goldman A;. Protein Eng 1992;5:197-211. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF012770.5
Method:: HMM

Select item 4068625.