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trehalose-6-phosphate synthase
Members of this family belong to glycosyl transferase family 20 [1]. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex, [2]. [1]. 9334165. A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities. Campbell JA, Davies GJ, Bulone V, Henrissat B;. Biochem J 1997;326:929-939. [2]. 8045430. Analysis of the otsBA operon for osmoregulatory trehalose synthesis in Escherichia coli and homology of the OtsA and OtsB proteins to the yeast trehalose-6-phosphate synthase/phosphatase complex. Kaasen I, McDougall J, Strom AR;. Gene 1994;145:9-15. (from Pfam)
trehalose-6-phosphate synthase catalyzes the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a uridine diphosphate-glucose donor
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