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2OG-Fe(II) oxygenase
This family of bacterial sequences is predicted to catalyse oxidative de-methylation of damaged bases in DNA. [1]. 23022560. A new family of bacterial DNA repair proteins annotated by the integration of non-homology, distant homology and structural bioinformatic methods. Mello LV, Rigden DJ;. FEBS Lett. 2012; [Epub ahead of print] (from Pfam)
2OG-Fe(II) oxygenase belonging to the large and diverse Fe(II)- and 2-oxoglutarate (2-OG)-dependent dioxygenase superfamily that share a common reaction mechanism, using Fe(II) and the cosubstrate 2-OG in the active site to activate oxygen, resulting in the two-electron oxidation of the target substrate
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