Protein Family Models

This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC [1]. SecD and SecF are required to maintain a proton motive force [2]. This alignment encompasses a -GG- motif typically found in N-terminal half of the SecD/SecF proteins . [1]. 9694879. SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins. Bolhuis A, Broekhuizen CP, Sorokin A, van Roosmalen ML, Venema G, Bron S, Quax WJ, van Dijl JM;. J Biol Chem 1998;273:21217-21224. [2]. 8112309. SecD and SecF are required for the proton electrochemical gradient stimulation of preprotein translocation. Arkowitz RA, Wickner W;. EMBO J 1994;13:954-963. (from Pfam)

Date:

2024-10-16

This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC [1]. SecD and SecF are required to maintain a proton motive force [2]. [1]. 9694879. SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins. Bolhuis A, Broekhuizen CP, Sorokin A, van Roosmalen ML, Venema G, Bron S, Quax WJ, van Dijl JM;. J Biol Chem 1998;273:21217-21224. [2]. 8112309. SecD and SecF are required for the proton electrochemical gradient stimulation of preprotein translocation. Arkowitz RA, Wickner W;. EMBO J 1994;13:954-963. (from Pfam)

Date:

2024-10-16

protein translocase subunit SecF is part of the Sec protein translocase complex; SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA

Date:

2024-11-05

This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein.

Gene:

secF

Date:

2024-06-04

The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins.

Date:

2019-09-10