Protein Family Models

This family includes several putative integral membrane proteins which have been predicted as the putative subunit of transporters for D-alanine or lactate (See Supplementary note 5 in [1]). [1]. 29769716. Mutant phenotypes for thousands of bacterial genes of unknown function. Price MN, Wetmore KM, Waters RJ, Callaghan M, Ray J, Liu H, Kuehl JV, Melnyk RA, Lamson JS, Suh Y, Carlson HK, Esquivel Z, Sadeeshkumar H, Chakraborty R, Zane GM, Rubin BE, Wall JD, Visel A, Bristow J, Blow MJ, Arkin AP, Deutschbauer AM;. Nature. 2018;557:503-509. (from Pfam)

Date:

2024-10-16

DUF4212 domain-containing protein similar to Shewanella oneidensis solute:sodium symporter small subunit

Date:

2018-02-22

Members of this family are highly hydrophobic bacterial proteins of about 90 amino acids in length. Members usually are found immediately upstream (sometimes fused to) a member of the solute:sodium symporter family, and therefore are a putative sodium:solute symporter small subunit. Members tend to be found in aquatic species, especially those from marine or other high salt environments. Substrates identified for various members include acetate, pyruvate, D-alanine, L-lactate and L-malate.

Date:

2023-12-03