Protein Family Models for Protein (Select 2197366949) - Protein Family Models

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Links from Protein

Items: 7

Select item 4135351.

This family represents a small domain of the E2 subunit of 2-oxo-acid dehydrogenases responsible for the binding of the E3 subunit. [1]. 8805537. Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase. Mande SS, Sarfaty S, Allen MD, Perham RN, Hol WG;. Structure 1996;4:277-286. (from Pfam)

GO Terms:

Molecular Function:: acyltransferase activity (GO:0016746)

Date:: 2024-10-16

Family Accession:: NF014832.5
Method:: HMM

Select item 4113132.

2-oxo acid dehydrogenase subunit E2

These proteins contain one to three copies of a lipoyl binding domain followed by the catalytic domain. [1]. 8487300. Refined crystal structure of the catalytic domain of dihysrolipoyl transacetylase (E2P) from azotobacter vineelandii at 2.6 angstroms resolution. Mattevi A, Obmolova G, Kalk KH, Westphal AH, De Kok A, Hol WG;. J Mol Biol 1993;230:1183-1199. (from Pfam)

GO Terms:

Molecular Function:: acyltransferase activity (GO:0016746)

Date:: 2024-10-29

Family Accession:: NF012424.5
Method:: HMM

Select item 3894883.

new record, indexing in progress

Family Accession:

Select item 3886474.

new record, indexing in progress

Family Accession:

Select item 3492235.

new record, indexing in progress

Family Accession:

Select item 3465986.

new record, indexing in progress

Family Accession:

Select item 519297.

2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase

This model represents an Actinobacterial clade of E2 enzyme, a component of the 2-oxoglutarate dehydrogenase complex involved in the TCA cycle. These proteins have multiple domains including the catalytic domain (PF00198), one or two biotin domains (PF00364) and an E3-component binding domain (PF02817).