Protein Family Models for Protein (Select 2219747681) - Protein Family Models

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Items: 4

Select item 4174471.

type IV secretion system protein

Members of this family are components of the type IV secretion system. They mediate intracellular transfer of macromolecules via a mechanism ancestrally related to that of bacterial conjugation machineries [1][2]. [1]. 15546668. Type IV secretion: the Agrobacterium VirB/D4 and related conjugation systems. Christie PJ;. Biochim Biophys Acta 2004;1694:219-234. [2]. 14673074. Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101. Yeo HJ, Yuan Q, Beck MR, Baron C, Waksman G;. Proc Natl Acad Sci U S A 2003;100:15947-15952. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF019608.5
Method:: HMM

Select item 3944402.

new record, indexing in progress

Family Accession:

Select item 3535203.

new record, indexing in progress

Family Accession:

Select item 507774.

P-type DNA transfer protein VirB5

The VirB5 protein is involved in the type IV DNA secretion systems typified by the Agrobacterium Ti plasmid vir system where it interacts with several other proteins essential for proper pilus formation [1]. VirB5 is homologous to the IncN (N-type) conjugation system protein TraC [2] as well as the P-type protein TrbJ and the F-type protein TraE [3].