Protein Family Models

Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein. [1]. 11897024. Extensive domain shuffling in transcription regulators of DNA viruses and implications for the origin of fungal APSES transcription factors. Iyer LM, Koonin EV, Aravind L;. Genome Biol 2002;3:RESEARCH0012. (from Pfam)

Date:

2024-10-16

This domain was called the KilAC domain by Iyer and colleagues [2]. [1]. 7669337. The tripartite immunity system of phages P1 and P7. Heinrich J, Velleman M, Schuster H;. FEMS Microbiol Rev 1995;17:121-126. [2]. 11897024. Extensive domain shuffling in transcription regulators of DNA viruses and implications for the origin of fungal APSES transcription factors. Iyer LM, Koonin EV, Aravind L;. Genome Biol 2002;3:RESEARCH0012. (from Pfam)

Date:

2024-10-16

Rha family transcriptional regulator is a regulatory protein found in temperate phage and bacterial prophage regions

Date:

2019-05-01