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TFIIB-type zinc ribbon-containing protein
The transcription factor TFIIB contains a zinc-binding motif near the N-terminus. This domain is involved in the interaction with RNA pol II and TFIIF and plays a crucial role in selecting the transcription initiation site. The domain adopts a zinc ribbon like structure [1]. [1]. 11045620. Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription. Chen HT, Legault P, Glushka J, Omichinski JG, Scott RA;. Protein Sci 2000;9:1743-1752. (from Pfam)
Transcription factor TFIIB repeat
transcription initiation factor IIB
transcription initiation factor IIB (TFIIB) stabilizes TBP binding to an archaeal box-A promoter; also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB)
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