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transposase
Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with Pfam:PF01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function. (from Pfam)
IS110 family transposase
Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family Pfam:PF02371. [1]. 1324903. A Coxiella burnetti repeated DNA element resembling a bacterial insertion sequence. Hoover TA, Vodkin MH, Williams JC;. J Bacteriol 1992;174:5540-5548. [2]. 2403542. Sequence analysis of the inversion region containing the pilin genes of Moraxella bovis. Fulks KA, Marrs CF, Stevens SP, Green MR;. J Bacteriol 1990;172:310-316. (from Pfam)
IS110 family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism
Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type transposases, which are encoded by the IS110 family elements.
IS110.curated: hypothetical protein
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