Protein Family Models

Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts [2]. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif [1]. [1]. 9546395. A novel and ubiquitous system for membrane targeting and secretion of cofactor-containing proteins. Weiner JH, Bilous PT, Shaw GM, Lubitz SP, Frost L, Thomas GH, Cole JA, Turner RJ;. Cell 1998;93:93-101. [2]. 9367960. Sec-independent protein translocation by the maize Hcf106 protein. Settles AM, Yonetani A, Baron A, Bush DR, Cline K, Martienssen R;. Science 1997;278:1467-1470. (from Pfam)

Date:

2024-10-16

Part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors

Gene:

tatA

Date:

2022-10-11