Protein Family Models for Protein (Select 2443344406) - Protein Family Models

Warning: The NCBI web site requires JavaScript to function. more...

Links from Protein

Items: 6

Select item 4182111.

This domain is found at the C-terminus of adenylosuccinate lyase(ASL; PurB in E. coli). It has been identified in bacteria, eukaryotes and archaea and is found together with the lyase domain Pfam:PF00206. ASL catalyses the cleavage of succinylaminoimidazole carboxamide ribotide to aminoimidazole carboxamide ribotide and fumarate and the cleavage of adenylosuccinate to adenylate and fumarate [1]. [1]. 8530047. Characterization of the cDNA and the gene encoding murine adenylosuccinate lyase. Wong LJ, O'Brien WE;. Genomics 1995;28:341-343. (from Pfam)

GO Terms:

Molecular Function:: N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (GO:0004018)

Biological Process:: IMP biosynthetic process (GO:0006188)

Date:: 2024-10-16

Family Accession:: NF019929.5
Method:: HMM

Select item 4108842.

lyase family protein

Members of this family include fumarate hydratase, L-aspartate ammonia-lyase, argininosuccinate lyase, and adenylosuccinate lyase. All are classified as lyases, meaning these enzymes break a bond by an eliminating reaction that does not involve hydrolysis or oxidation.