Protein Family Models for Protein (Select 2486274955) - Protein Family Models

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Items: 4

Select item 4140761.

2-hydroxycarboxylate transporter family protein

The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate [1]. [1]. 16339740. The 2-hydroxycarboxylate transporter family: physiology, structure, and mechanism. Sobczak I, Lolkema JS;. Microbiol Mol Biol Rev. 2005;69:665-695. [2]. 15853816. Secondary transporters of the 2HCT family contain two homologous domains with inverted membrane topology and trans re-entrant loops. Lolkema JS, Sobczak I, Slotboom DJ;. FEBS J. 2005;272:2334-2344. (from Pfam)

GO Terms:

Molecular Function:: organic anion transmembrane transporter activity (GO:0008514)

Biological Process:: organic anion transport (GO:0015711)

Cellular Component:: membrane (GO:0016020)

Date:: 2024-10-16

Family Accession:: NF015355.5
Method:: HMM

Select item 3898722.

new record, indexing in progress

Family Accession:

Select item 3489263.

new record, indexing in progress

Family Accession:

Select item 441574.

2-hydroxycarboxylate transporter family protein

2-hydroxycarboxylate transporter (2HCT) family protein functions in the metabolism of the di- and tricarboxylates malate and citrate, in fermentative pathways involving decarboxylation of malate or oxaloacetate; such as Streptococcus equinus L-malate permease