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AraC family transcriptional regulator ligand-binding domain-containing protein
AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, Pfam:PF00165, and this dimerisation domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3]. [1]. 9600837. Arm-domain interactions in AraC. Saviola B, Seabold R, Schleif RF;. J Mol Biol 1998;278:539-548. [2]. 11286551. Mapping arm-DNA-binding domain interactions in AraC. Wu M, Schleif R;. J Mol Biol. 2001;307:1001-1009. [3]. 12596232. AraC protein: a love-hate relationship. Schleif R;. Bioessays. 2003;25:274-282. (from Pfam)
helix-turn-helix domain-containing protein
AraC family transcriptional regulator
AraC family transcriptional regulator controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence
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