Protein Family Models

This family comprises the C-terminal domain of saccharopine dehydrogenase. In some organisms this enzyme is found as a bifunctional polypeptide with lysine ketoglutarate reductase. The saccharopine dehydrogenase can also function as a saccharopine reductase. [1]. 8885833. Three-dimensional structure of meso-diaminopimelic acid dehydrogenase from Corynebacterium glutamicum. Scapin G, Reddy SG, Blanchard JS;. Biochemistry. 1996;35:13540-13551. [2]. 11080625. Crystal structure of saccharopine reductase from Magnaporthe grisea, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis. Johansson E, Steffens JJ, Lindqvist Y, Schneider G;. Structure Fold Des 2000;8:1037-1047. (from Pfam)

Date:

2024-10-16

This family contains the NADP binding domain of saccharopine dehydrogenase. In some organisms this enzyme is found as a bifunctional polypeptide with lysine ketoglutarate reductase. The saccharopine dehydrogenase can also function as a saccharopine reductase. [1]. 11080625. Crystal structure of saccharopine reductase from Magnaporthe grisea, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis. Johansson E, Steffens JJ, Lindqvist Y, Schneider G;. Structure Fold Des 2000;8:1037-1047. [2]. 11354603. Lysine metabolism in higher plants. Azevedo RA, Lea PJ;. Amino Acids 2001;20:261-279. (from Pfam)

Date:

2024-10-16

saccharopine dehydrogenase family protein such as saccharopine dehydrogenase, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis that catalyzes the reversible conversion of glutamate and alpha-aminoadipic-delta-semialdehyde to saccharopine

Date:

2024-11-25