Protein Family Models for Protein (Select 2519095107) - Protein Family Models

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Items: 5

Select item 4115581.

Pyroglutamyl peptidase

Date:: 2024-08-14

Family Accession:: NF013624.5
Method:: HMM

Select item 3896632.

new record, indexing in progress

Family Accession:

Select item 3492523.

new record, indexing in progress

Family Accession:

Select item 1861684.

pyroglutamyl-peptidase I

Date:: 2020-10-26

Family Accession:: NF009676.0
Method:: HMM

Select item 202905.

pyroglutamyl-peptidase I

Alternate names include pyroglutamate aminopeptidase, pyrrolidone-carboxylate peptidase, and 5-oxoprolyl-peptidase. It removes pyroglutamate (pyrrolidone-carboxylate, a modified glutamine) that can otherwise block hydrolysis of a polypeptide at the amino end, and so can be extremely useful in the biochemical studies of proteins. The biological role in the various species in which it is found is not fully understood. The enzyme appears to be a homodimer. It does not closely resemble any other peptidases.