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Links from Protein

Items: 5

1.

UDP-3-O-acyl-N-acetylglucosamine deacetylase

The enzymes in this family catalyse the second step in the biosynthetic pathway for lipid A. [1]. 10753902. Antibacterial agents that target lipid A biosynthesis in. gram-negative bacteria. Inhibition of diverse. UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases. by substrate analogs containing zinc binding motifs.. Jackman JE, Fierke CA, Tumey LN, Pirrung M, Uchiyama T, Tahir. SH, Hindsgaul O, Raetz CR;. J Biol Chem 2000;275:11002-11009. (from Pfam)

GO Terms:
Molecular Function:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity (GO:0008759)
Biological Process:
lipid A biosynthetic process (GO:0009245)
Date:
2024-08-14
Family Accession:
NF015299.5
Method:
HMM
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.

UDP-3-O-acyl-N-acetylglucosamine deacetylase

UDP-3-O-acyl-N-acetylglucosamine deacetylase catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis

Date:
2017-06-22
Family Accession:
10002399
Method:
Sparcle
5.

UDP-3-O-acyl-N-acetylglucosamine deacetylase

UDP-3-O-acyl-N-acetylglucosamine deacetylase from E. coli, LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability.

Gene:
lpxC
GO Terms:
Molecular Function:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity (GO:0008759)
Biological Process:
lipid A biosynthetic process (GO:0009245)
Date:
2023-06-23
Family Accession:
TIGR00325.1
Method:
HMM
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