Protein Family Models for Protein (Select 2530633220) - Protein Family Models

Select item 4307231.

This domain is found towards the C terminus of Beta-glucuronidase from Formosa agariphila (P17_GH2) and similar proteins mainly from bacteria and fungi. P17_GH2 is involved in the degradation of the polysaccharide ulvan. The function of this domain, which shows an all-beta structure, is unknown [1]. [1]. 31285597. A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan. Reisky L, Prechoux A, Zuhlke MK, Baumgen M, Robb CS, Gerlach N, Roret T, Stanetty C, Larocque R, Michel G, Song T, Markert S, Unfried F, Mihovilovic MD, Trautwein-Schult A, Becher D, Schweder T, Bornscheuer UT, Hehemann JH;. Nat Chem Biol. 2019;15:803-812. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF027673.5
Method:: HMM

Select item 4273372.

Glycoside hydrolase family 2 C-terminal domain 5

Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme [1]. [1]. 27599737. Structural studies of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d. Rutkiewicz-Krotewicz M, Pietrzyk-Brzezinska AJ, Sekula B, Cieslinski H, Wierzbicka-Wos A, Kur J, Bujacz A;. Acta Crystallogr D Struct Biol. 2016;72:1049-1061. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF037850.5
Method:: HMM

Select item 4135373.

glycoside hydrolase family 2 TIM barrel-domain containing protein

This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. [1]. 8008071. Three-dimensional structure of beta-galactosidase from E. coli. Jacobson RH, Zhang XJ, DuBose RF, Matthews BW;. Nature. 1994;369:761-766. (from Pfam)

GO Terms:

Molecular Function:: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)

Biological Process:: carbohydrate metabolic process (GO:0005975)

Date:: 2024-10-16

Family Accession:: NF014850.5
Method:: HMM

Select item 4130684.

sugar-binding domain-containing protein

This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction. [1]. 8008071. Three-dimensional structure of beta-galactosidase from E. coli. Jacobson RH, Zhang XJ, DuBose RF, Matthews BW;. Nature. 1994;369:761-766. (from Pfam)

GO Terms:

Molecular Function:: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)

Biological Process:: carbohydrate metabolic process (GO:0005975)

Date:: 2024-10-16

Family Accession:: NF014851.5
Method:: HMM

Select item 4109565.

Glycosyl hydrolases family 2

GO Terms:

Molecular Function:: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)

Biological Process:: carbohydrate metabolic process (GO:0005975)

Date:: 2024-10-16

Family Accession:: NF012906.5
Method:: HMM

Select item 4046436.