Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
tetratricopeptide repeat protein
This family is found predominantly at the C-terminus of transglutaminase enzyme core regions. (from Pfam)
CDC27 family protein
Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes [1, 2]. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20 [3]. [1]. 12049731. The anaphase-promoting complex: proteolysis in mitosis and beyond. Peters JM;. Mol Cell. 2002;9:931-943. [2]. 16896351. The anaphase promoting complex/cyclosome: a machine designed to destroy. Peters JM;. Nat Rev Mol Cell Biol. 2006;7:644-656. [3]. 12956947. TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. Vodermaier HC, Gieffers C, Maurer-Stroh S, Eisenhaber F, Peters JM;. Curr Biol. 2003;13:1459-1468. (from Pfam)
This Pfam entry includes tetratricopeptide-like repeats found in the LcrH/SycD-like chaperones [1]. [1]. 12799000. Tetratricopeptide-like repeats in type-III-secretion chaperones and regulators. Pallen MJ, Francis MS, Futterer K;. FEMS Microbiol Lett 2003;223:53-60. (from Pfam)
This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by Pfam:PF00515. [1]. 7667876. Tetratrico peptide repeat interactions: to TPR or not to TPR?. Lamb JR, Tugendreich S, Hieter P;. Trends Biochem Sci 1995;20:257-259. [2]. 9482716. The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions. Das AK, Cohen PW, Barford D;. EMBO J 1998;17:1192-1199. (from Pfam)
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on