Protein Family Models for Protein (Select 2554498074) - Protein Family Models

Select item 4359621.

phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways

Date:: 2024-07-25

Family Accession:: 11414960
Method:: Sparcle

Select item 4358482.

phosphopyruvate hydratase

Enolase (phosphopyruvate hydratase, EC 4.2.1.11) is a widely distributed cytosolic enzyme with a critical role in glycolysis. In bacteria, it occurs in nearly every species. Enolases from multiple lineages have been reported to exhibit surface expression and to have virulence-related moonlighting functions, such as binding to fibrinogen or other host proteins.

Gene:: eno

GO Terms:

Cellular Component:: phosphopyruvate hydratase complex (GO:0000015)

Molecular Function:: magnesium ion binding (GO:0000287)

Molecular Function:: phosphopyruvate hydratase activity (GO:0004634)

Biological Process:: glycolytic process (GO:0006096)

Date:: 2024-12-13

Family Accession:: TIGR01060.2
Method:: HMM

Select item 4179713.

Methylaspartate ammonia-lyase C-terminus

Methylaspartate ammonia-lyase EC:4.3.1.2 catalyses the second step of fermentation of glutamate. It is a homodimer. This family represents the C-terminal region of Methylaspartate ammonia-lyase and contains a TIM barrel fold similar to the Pfam:PF01188. This family represents the catalytic domain and contains a metal binding site [2]. [1]. 1420191. Cloning, sequencing, and expression in Escherichia coli of the Clostridium tetanomorphum gene encoding beta-methylaspartase and characterization of the recombinant protein. Goda SK, Minton NP, Botting NP, Gani D;. Biochemistry 1992;31:10747-10756. [2]. 11748244. The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step. Asuncion M, Blankenfeldt W, Barlow JN, Gani D, Naismith JH;. J Biol Chem 2002;277:8306-8311. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF019119.5
Method:: HMM

Select item 4143864.

Enolase, N-terminal domain

Date:: 2024-08-14

Family Accession:: NF015885.5
Method:: HMM

Select item 4117495.

Enolase, C-terminal TIM barrel domain

Date:: 2024-08-14

Family Accession:: NF012341.5
Method:: HMM

Select item 3956106.