Protein Family Models

TamB is an integral inner membrane protein that forms a complex - the translocation and assembly module or TAM [2] - with the outer membrane protein, TamA. TAM is responsible for the efficient secretion of the adhesin protein Ag43 in E.coli K-12 [1]. [1]. 22466966. Discovery of an archetypal protein transport system in bacterial outer membranes. Selkrig J, Mosbahi K, Webb CT, Belousoff MJ, Perry AJ, Wells TJ, Morris F, Leyton DL, Totsika M, Phan MD, Celik N, Kelly M, Oates C, Hartland EL, Robins-Browne RM, Ramarathinam SH, Purcell AW, Schembri MA, Strugnell RA, Henderson IR, Walker D, Lithgow T;. Nat Struct Mol Biol. 2012;19:506-510. [2]. 25195908. Recombinant expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal DUF490(963-1138) domain of TamB from Escherichia coli. Josts I, Grinter R, Kelly SM, Mosbahi K, Roszak A, Cogdell R, Smith BO, Byron O, Walker D;. Acta Crystallogr F Struct Biol Commun. 2014;70:1272-1275. (from Pfam)

Date:

2024-10-16

TamB family protein similar to translocation/assembly module TamB that is a part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in the translocation of autotransporters across the outer membrane

Date:

2022-12-06