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Sir2- and TIR-associating SLOG family
Family in the SLOG superfamily, associating with predicted Sir2- and TIR-like effector domains. Members of this family are predicted to functions as sensors of nucleotide or nucleotide-derived ligands, which are likely processed or modified by the associating effectors [1]. [1]. 26590262. Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling. Burroughs AM, Zhang D, Schaffer DE, Iyer LM, Aravind L;. Nucleic Acids Res. 2015;43:10633-10654. (from Pfam)
SLOG cluster2
Family in the SLOG superfamily, observed associating with distinct effector domains including the patatin lipase or a protein containing one enzymatically active and one inactive copy of the TIR domain [1]. [1]. 26590262. Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling. Burroughs AM, Zhang D, Schaffer DE, Iyer LM, Aravind L;. Nucleic Acids Res. 2015;43:10633-10654. (from Pfam)
SIR2 family protein
This family of proteins are related to the sirtuins. (from Pfam)
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