Protein Family Models for Protein (Select 2731280296) - Protein Family Models

Select item 4250841.

helix-turn-helix domain-containing protein

Date:: 2024-08-14

Family Accession:: NF024954.5
Method:: HMM

Select item 4233832.

integrase core domain-containing protein

GO Terms:

Biological Process:: DNA integration (GO:0015074)

Date:: 2024-08-14

Family Accession:: NF025063.5
Method:: HMM

Select item 4208743.

leucine zipper domain-containing protein

This is the upstream region of the conjoined ORF AB of insertion element 481. The significance of IS481 in the detection of Bordetella pertussis is discussed in [1]. The B portion of the ORF AB carries the transposase activity in family rve, PFAM:PF00665. [1]. 17065269. Prevalence and sequence variants of IS481 in Bordetella bronchiseptica: implications for IS481-based detection of Bordetella pertussis. Register KB, Sanden GN;. J Clin Microbiol. 2006;44:4577-4583. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF024412.5
Method:: HMM

Select item 4111094.

DDE-type integrase/transposase/recombinase

Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain Pfam:PF02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain Pfam:PF00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyses the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site [1]. [1]. 7801124. Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases [see comments]. Dyda F, Hickman AB, Jenkins TM, Engelman A, Craigie R, Davies DR;. Science 1994;266:1981-1986. (from Pfam)

GO Terms:

Biological Process:: DNA integration (GO:0015074)

Date:: 2024-10-16

Family Accession:: NF012870.5
Method:: HMM

Select item 4022555.

new record, indexing in progress

Family Accession:

Select item 4020796.

new record, indexing in progress

Family Accession:

Select item 4009907.

new record, indexing in progress

Family Accession:

Select item 3885558.

new record, indexing in progress

Family Accession:

Select item 197879.

IS481 family transposase

null

GO Terms:

Molecular Function:: transposase activity (GO:0004803)

Date:: 2021-03-03

Family Accession:: NF033577.2
Method:: HMM

Select item 1675510.

IS3_IS3_ORF2.curated: hypothetical protein

Date:: 2019-09-10

Family Accession:: NF012068.0
Method:: HMM

Select item 1594111.

IS481.original: hypothetical protein

Date:: 2019-09-10

Family Accession:: NF012077.0
Method:: HMM

Select item 1593912.

IS3_IS3_combined.original: hypothetical protein

Date:: 2019-09-10

Family Accession:: NF012069.0
Method:: HMM

Protein Family Models

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