Protein Family Models

This family includes the C-terminal region of flagellar motor switch proteins FliN and FliM. It is associated with family FliM, Pfam:PF02154 and family FliN_N Pfam:PF16973. [1]. 1447979. Identification and characterization of FliY, a novel component of the Bacillus subtilis flagellar switch complex. Bischoff DS, Ordal GW;. Mol Microbiol 1992;6:2715-2723. [2]. 8885278. Salmonella spp. are cytotoxic for cultured macrophages. Chen LM, Kaniga K, Galan JE;. Mol Microbiol 1996;21:1101-1115. [3]. 15805535. Crystal structure of the flagellar rotor protein FliN from Thermotoga maritima. Brown PN, Mathews MA, Joss LA, Hill CP, Blair DF;. J Bacteriol. 2005;187:2890-2902. [4]. 16547037. Organization of FliN subunits in the flagellar motor of Escherichia coli. Paul K, Blair DF;. J Bacteriol. 2006;188:2502-2511. (from Pfam)

Date:

2024-10-16

Proteins that consist largely of the domain described by this HMM for this protein family can be designated flagellar motor switch protein FliN. Longer proteins in which this region is a C-terminal domain typically are designated FliY. More distantly related sequences, outside the scope of this family, are associated with type III secretion and include the surface presentation of antigens protein SpaO required or invasion of host cells by Salmonella enterica.

Gene:

fliN

Date:

2024-06-04