Protein Family Models for Protein (Select 2771595271) - Protein Family Models

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Items: 3

Select item 4113931.

pseudouridine synthase

Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD Swiss:P33643, a pseudouridylate synthase that converts specific uracils to pseudouridine in 23S rRNA. RluA from E. coli converts bases in both rRNA and tRNA [1]. [1]. 7493321. A dual-specificity pseudouridine synthase: an Escherichia coli. synthase purified and cloned on the basis of its specificity for. psi 746 in 23S RNA is also specific for psi 32 in tRNA(phe).. Wrzesinski J, Nurse K, Bakin A, Lane BG, Ofengand J;. RNA 1995;1:437-448. (from Pfam)

GO Terms:

Biological Process:: pseudouridine synthesis (GO:0001522)

Molecular Function:: RNA binding (GO:0003723)

Biological Process:: RNA modification (GO:0009451)

Molecular Function:: pseudouridine synthase activity (GO:0009982)

Date:: 2024-08-14

Family Accession:: NF013045.5
Method:: HMM

Select item 3891642.

new record, indexing in progress

Family Accession:

Select item 163833.

pseudouridine synthase

This HMM identifies panels of pseudouridine synthase enzymes that RNA modifications involved in maturing the protein translation apparatus. Counts per genome vary: two in Staphylococcus aureus, three in Pseudomonas putida, four in E. coli, etc.

GO Terms: