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Acyl-CoA dehydrogenase, C-terminal domain
acyl-CoA dehydrogenase family protein
The N-terminal domain of Acyl-CoA dehydrogenase is an all-alpha domain. [1]. 7857927. Three-dimensional structure of butyryl-CoA dehydrogenase from Megasphaera elsdenii. Djordjevic S, Pace CP, Stankovich MT, Kim JJ;. Biochemistry. 1995;34:2163-2171. [2]. 8356049. Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate. Kim JJ, Wang M, Paschke R;. Proc Natl Acad Sci U S A 1993;90:7523-7527. (from Pfam)
Central domain of Acyl-CoA dehydrogenase has a beta-barrel fold. [1]. 7857927. Three-dimensional structure of butyryl-CoA dehydrogenase from Megasphaera elsdenii. Djordjevic S, Pace CP, Stankovich MT, Kim JJ;. Biochemistry. 1995;34:2163-2171. [2]. 8356049. Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate. Kim JJ, Wang M, Paschke R;. Proc Natl Acad Sci U S A 1993;90:7523-7527. (from Pfam)
C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle. [1]. 7857927. Three-dimensional structure of butyryl-CoA dehydrogenase from Megasphaera elsdenii. Djordjevic S, Pace CP, Stankovich MT, Kim JJ;. Biochemistry. 1995;34:2163-2171. [2]. 8356049. Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate. Kim JJ, Wang M, Paschke R;. Proc Natl Acad Sci U S A 1993;90:7523-7527. [3]. 11514662. Sequence-structure analysis of FAD-containing proteins. Dym O, Eisenberg D;. Protein Sci 2001;10:1712-1728. (from Pfam)
acyl-CoA dehydrogenase family protein similar to acyl-CoA dehydrogenase that catalyzes the alpha, beta dehydrogenation of an acyl-CoA to form 2,3-dehydroacyl-CoA requiring an acceptor such as FAD, which becomes reduced..
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