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aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
DegT/DnrJ/EryC1/StrS family aminotransferase
The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA Swiss:P72454, StsC Swiss:P77952 and StsS [1]. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyses the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin [1]. [1]. 9238101. Identification of stsC, the gene encoding the L-glutamine:scyllo-inosose aminotransferase from streptomycin-producing Streptomycetes. Ahlert J, Distler J, Mansouri K, Piepersberg W;. Arch Microbiol 1997;168:102-113. (from Pfam)
pyridoxal phosphate-dependent aminotransferase
pyridoxal phosphate-dependent aminotransferase such as glutamate-pyruvate aminotransferase AlaA that catalyzes the transamination of pyruvate by glutamate, leading to the formation of L-alanine and 2-oxoglutarate
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