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tRNA (Guanine-1)-methyltransferase
This is a family of tRNA (Guanine-1)-methyltransferases EC:2.1.1.31. In E.coli K12 this enzyme catalyses the conversion of a guanosine residue to N1-methylguanine in position 37, next to the anticodon, in tRNA [1]. [1]. 6337136. Purification and characterization of transfer RNA (guanine- 1)methyltransferase from Escherichia coli. Hjalmarsson KJ, Bystrom AS, Bjork GR;. J Biol Chem 1983;258:1343-1351. (from Pfam)
tRNA (guanine(37)-N(1))-methyltransferase
tRNA (guanine(37)-N(1))-methyltransferase specifically methylates guanosine-37 in various tRNAs
tRNA (guanosine(37)-N1)-methyltransferase TrmD
Methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
This model is specfic for the tRNA modification enzyme tRNA (guanine-N1)-methyltransferase (trmD). This enzyme methylates guanosime-37 in a number of tRNAs.The enzyme's catalytic activity is as follows: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.
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