Predicted to function as a sensor domain, sensing nucleotides or nucleotide derivatives generated by bacterial adenylyl/guanylyl cyclase domains. The sensing of ligands by AGS-C is predicted to activate effectors deployed by a class of conflict systems which are reliant on the on the production and sensing of the nucleotide second messengers [1]. [1]. 26590262. Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling. Burroughs AM, Zhang D, Schaffer DE, Iyer LM, Aravind L;. Nucleic Acids Res. 2015;43:10633-10654. (from Pfam)
- Date:
- 2024-11-19