Protein Family Models for Protein (Select 2796465492) - Protein Family Models

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Items: 5

Select item 4240291.

tetratricopeptide repeat protein

Date:: 2024-08-14

Family Accession:: NF024806.5
Method:: HMM

Select item 4226592.

trypsin-like peptidase domain-containing protein

This family includes trypsin-like peptidase domains. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024758.5
Method:: HMM

Select item 4225783.

tetratricopeptide repeat protein

Date:: 2024-08-14

Family Accession:: NF025910.5
Method:: HMM

Select item 4217494.

CDC27 family protein

Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes [1, 2]. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20 [3]. [1]. 12049731. The anaphase-promoting complex: proteolysis in mitosis and beyond. Peters JM;. Mol Cell. 2002;9:931-943. [2]. 16896351. The anaphase promoting complex/cyclosome: a machine designed to destroy. Peters JM;. Nat Rev Mol Cell Biol. 2006;7:644-656. [3]. 12956947. TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. Vodermaier HC, Gieffers C, Maurer-Stroh S, Eisenhaber F, Peters JM;. Curr Biol. 2003;13:1459-1468. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF024299.5
Method:: HMM

Select item 4156335.

Coatomer epsilon subunit

This family represents the epsilon subunit of the coatomer complex, which is involved in the regulation of intracellular protein trafficking between the endoplasmic reticulum and the Golgi complex [1]. [1]. 10469566. Segregation of COPI-rich and anterograde-cargo-rich domains in endoplasmic-reticulum-to-Golgi transport complexes. Shima DT, Scales SJ, Kreis TE, Pepperkok R;. Curr Biol 1999;9:821-824. (from Pfam)